Tapentadol is partly metabolized with the hepatic enzymes CYP2C9, CYP2C19, and CYP2D6 so it innately has interactions with drugs that increase or repress the exercise/expression of a number of of these enzymes, along with with substrates of those enzymes (as a consequence of Opposition to the enzyme); some enzyme mediators/substrates https://henryb931txt3.wikicarrier.com/user