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Pacijente treba pažljivo pratiti u cilju prepoznavanja znakova i simptoma respiratorne depresije i sedacije. U ovom pogledu se preporučuje informisanje pacijenata i njihovih staratelja (kada je to primenljivo) o značajnosti prepoznavanja ovih simptoma (videti odeljak four.five). The FDA restricts use of tramadol in children as a result of critical threat https://bettersleepuk.com/product/carisoprodol-soma-pain-500mg-tablets/

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