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Pentobarbital will lower the extent or effect of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. pentobarbital raises levels of vortioxetine by increasing metabolism. Modify Therapy/Keep an eye on Closely. Look at increasing the vortioxetine dose when coadministered with robust CYP inducers for >fourteen days; to not exceed three occasions https://edwinu853pwd9.bligblogging.com/profile


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